GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
别名:
CAT-2, CAT2
物种:
Human GIT2 (9815), Mouse Git2 (26431), Rat Git2 (304546), domestic cat GIT2 (101093054), Horse GIT2 (100066470), cow GIT2 (516048), dog GIT2 (477520), domestic guinea pig Git2 (100727065), chicken GIT2 (374035), naked mole-rat Git2 (101702496) ...展开
UniProtKB ID:
基因ID:
- Human(9815) Summary: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]
- Mouse(26431) G protein-coupled receptor kinase-interactor 2
- Rat(304546) G protein-coupled receptor kinase interacting ArfGAP 2
- domestic cat(101093054) G protein-coupled receptor kinase interacting ArfGAP 2
- Horse(100066470) G protein-coupled receptor kinase interacting ArfGAP 2
- cow(516048) G protein-coupled receptor kinase interacting ArfGAP 2
- dog(477520) G protein-coupled receptor kinase interacting ArfGAP 2
- domestic guinea pig(100727065) G protein-coupled receptor kinase interacting ArfGAP 2
- chicken(374035) G protein-coupled receptor kinase interactor 2
- naked mole-rat(101702496) G protein-coupled receptor kinase interacting ArfGAP 2
- sheep(101121803) G protein-coupled receptor kinase interacting ArfGAP 2
- Domestic Rabbit(100348106) G protein-coupled receptor kinase interacting ArfGAP 2
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Antibodies
货号
说明
物种反应性
应用
Anti-GIT2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Monoclonal Anti-GIT2 antibody produced in mouse, clone 1B2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Monoclonal Anti-GIT2 antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-GIT2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-GIT2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
western blot
western blot