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Merck
CN

GCDH

glutaryl-CoA dehydrogenase

别名:
ACAD5, GCD
物种:
UniProtKB ID:
基因ID:
  • Human(2639) Summary: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
  • Mouse(270076) glutaryl-Coenzyme A dehydrogenase
  • Rat(364975) glutaryl-CoA dehydrogenase
  • Zebrafish(393860) glutaryl-Coenzyme A dehydrogenase
  • sheep(101122190) glutaryl-CoA dehydrogenase
  • chicken(771098) glutaryl-CoA dehydrogenase
  • domestic cat(101086880) glutaryl-CoA dehydrogenase
  • dog(476696) glutaryl-CoA dehydrogenase
  • domestic guinea pig(100714939) glutaryl-CoA dehydrogenase
  • cow(506310) glutaryl-CoA dehydrogenase
  • Horse(100063310) glutaryl-CoA dehydrogenase
  • Domestic Rabbit(100343376) glutaryl-CoA dehydrogenase
  • naked mole-rat(101718348) glutaryl-CoA dehydrogenase

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Antibodies

货号
说明
物种反应性
应用
Anti-GCDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-GCDH antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
dog, horse, human, mouse, pig, rabbit, rat
应用
immunohistochemistry
western blot
抗-GCDH 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-GCDH antibody produced in rabbit, affinity isolated antibody,
物种反应性
guinea pig, human, mouse, rabbit, rat
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GCDH,
物种
human
MISSION® esiRNA, targeting mouse Gcdh,
物种
mouse