FGD1
FYVE, RhoGEF and PH domain containing 1
AAS, FGDY, MRXS16, ZFYVE3
Human FGD1 (2245), Mouse Fgd1 (14163), Rat Fgd1 (363460), sheep FGD1 (101117050), Zebrafish fgd1 (560305), cow FGD1 (100124501), domestic cat FGD1 (101094403), naked mole-rat Fgd1 (101720101), domestic guinea pig Fgd1 (100718541), dog FGD1 (491901)
- Human(2245) Summary: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
- Mouse(14163) FYVE, RhoGEF and PH domain containing 1
- Rat(363460) FYVE, RhoGEF and PH domain containing 1
- sheep(101117050) FYVE, RhoGEF and PH domain containing 1
- Zebrafish(560305) FYVE, RhoGEF and PH domain containing 1
- cow(100124501) FYVE, RhoGEF and PH domain containing 1
- domestic cat(101094403) FYVE, RhoGEF and PH domain containing 1
- naked mole-rat(101720101) FYVE, RhoGEF and PH domain containing 1
- domestic guinea pig(100718541) FYVE, RhoGEF and PH domain containing 1
- dog(491901) FYVE, RhoGEF and PH domain containing 1
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Antibodies
Anti-Fgd1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
Anti-FGD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
western blot
Anti-FGD1 antibody produced in rabbit, affinity isolated antibody,
human
immunohistochemistry
western blot
western blot