EWSR1
EWS RNA-binding protein 1
别名:
EWS, bK984G1.4
物种:
Human EWSR1 (2130), Mouse Ewsr1 (14030), Rat Ewsr1 (289752), naked mole-rat Ewsr1 (101697325), domestic guinea pig Ewsr1 (100718262), chicken EWSR1 (417022), sheep EWSR1 (101121203), cow EWSR1 (534073), Horse EWSR1 (100034010), domestic cat EWSR1 (101093398)
UniProtKB ID:
基因ID:
- Human(2130) Summary: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009]
- Mouse(14030) Ewing sarcoma breakpoint region 1
- Rat(289752) EWS RNA-binding protein 1
- naked mole-rat(101697325) EWS RNA-binding protein 1
- domestic guinea pig(100718262) EWS RNA-binding protein 1
- chicken(417022) Ewing sarcoma breakpoint region 1
- sheep(101121203) Ewing sarcoma breakpoint region 1
- cow(534073) Ewing sarcoma breakpoint region 1
- Horse(100034010) Ewing sarcoma breakpoint region 1
- domestic cat(101093398) Ewing sarcoma breakpoint region 1
- dog(609786) Ewing sarcoma breakpoint region 1
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Antibodies
货号
说明
物种反应性
应用
Anti-EWSR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-EWSR1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Anti-EWSR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-EWSR1 antibody produced in mouse, clone 5C10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-EWSR1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot