ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
别名:
erg-3, p55
物种:
Human ERG (2078), Mouse Erg (13876), Rat Erg (170909), chicken ERG (374146), Zebrafish erg (494073), Horse ERG (100051563), domestic cat ERG (101099895), dog ERG (487760), cow ERG (535231), Domestic Rabbit ERG (100347277) ...展开
UniProtKB ID:
基因ID:
- Human(2078) Summary: This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2012]
- Mouse(13876) avian erythroblastosis virus E-26 (v-ets) oncogene related
- Rat(170909) v-ets avian erythroblastosis virus E26 oncogene
- chicken(374146) v-ets erythroblastosis virus E26 oncogene homolog
- Zebrafish(494073) v-ets erythroblastosis virus E26 oncogene like (avian)
- Horse(100051563) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- domestic cat(101099895) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- dog(487760) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- cow(535231) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- Domestic Rabbit(100347277) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- sheep(101110646) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- naked mole-rat(101717041) v-ets erythroblastosis virus E26 oncogene homolog (avian)
- domestic guinea pig(100713723) v-ets erythroblastosis virus E26 oncogene homolog (avian)
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Antibodies
货号
说明
物种反应性
应用
Anti-ERG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-ERG antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-ERG antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rat
应用
western blot