DUSP2
dual specificity phosphatase 2
别名:
PAC-1, PAC1
物种:
Human DUSP2 (1844), Mouse Dusp2 (13537), Rat Dusp2 (311406), naked mole-rat Dusp2 (101702046), domestic guinea pig Dusp2 (100723186), cow DUSP2 (539140), domestic cat DUSP2 (101090684), sheep DUSP2 (101115699), Zebrafish dusp2 (445057), dog DUSP2 (611653)
UniProtKB ID:
基因ID:
- Human(1844) Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
- Mouse(13537) dual specificity phosphatase 2
- Rat(311406) dual specificity phosphatase 2
- naked mole-rat(101702046) dual specificity phosphatase 2
- domestic guinea pig(100723186) dual specificity phosphatase 2
- cow(539140) dual specificity phosphatase 2
- domestic cat(101090684) dual specificity phosphatase 2
- sheep(101115699) dual specificity phosphatase 2
- Zebrafish(445057) dual specificity phosphatase 2
- dog(611653) dual specificity phosphatase 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-DUSP2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
western blot
Anti-DUSP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence