DAND5
DAN domain family member 5, BMP antagonist
CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, SP1
Human DAND5 (199699), Mouse Dand5 (23863), Rat Dand5 (685719), domestic guinea pig Dand5 (100727384), Zebrafish dand5 (791454), dog DAND5 (484921), naked mole-rat Dand5 (101721262)
- Human(199699) Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
- Mouse(23863) DAN domain family, member 5
- Rat(685719) DAN domain family, member 5
- domestic guinea pig(100727384) DAN domain family member 5, BMP antagonist
- Zebrafish(791454) DAN domain family, member 5
- dog(484921) DAN domain family, member 5
- naked mole-rat(101721262) DAN domain family member 5, BMP antagonist
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Antibodies
Anti-DAND5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
Anti-DAND5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence