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Merck
CN

CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

别名:
CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B
物种:
UniProtKB ID:
基因ID:
  • Human(1589) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • dog(415124) cytochrome P450c21
  • cow(282425) cytochrome P450, family 21, subfamily A, polypeptide 2
  • chicken(429828) cytochrome P450, family 21, subfamily A, polypeptide 2

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Antibodies

货号
说明
物种反应性
应用
抗-CYP21A2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
抗-CYP21A2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-CYP21A2 (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-Cytochrome P450 21A2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
western blot