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Merck
CN

CTLA4

cytotoxic T-lymphocyte-associated protein 4

别名:
CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
物种:
UniProtKB ID:
基因ID:
  • Human(1493) Summary: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
  • Mouse(12477) cytotoxic T-lymphocyte-associated protein 4
  • Rat(63835) cytotoxic T-lymphocyte-associated protein 4
  • domestic guinea pig(100725760) cytotoxic T-lymphocyte-associated protein 4
  • naked mole-rat(101722788) cytotoxic T-lymphocyte-associated protein 4
  • cow(281732) cytotoxic T-lymphocyte-associated protein 4
  • dog(403696) cytotoxic T-lymphocyte-associated protein 4
  • domestic cat(493743) cytotoxic T-lymphocyte-associated protein 4
  • chicken(424106) cytotoxic T-lymphocyte-associated protein 4
  • Domestic Rabbit(100009412) cytotoxic T-lymphocyte-associated protein 4

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ELISA

货号
说明
物种
人类 CXCL16 ELISA 试剂盒, for serum, plasma, cell culture supernatant and urine,
物种
human
小鼠 CTLA-4 ELISA 试剂盒, for serum, plasma and cell culture supernatant,
物种
mouse

Antibodies

货号
说明
物种反应性
应用
Anti-CTLA4/CD152 Antibody, clone 1D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-CD152 (CTLA-4) Antibody (mouse), APC, clone UC10-4F10-11, clone UC10-4F10-11, 0.2 mg/mL, from hamster(Armenian),
物种反应性
mouse
应用
flow cytometry
Monoclonal Anti-CD152 antibody produced in mouse, ~1 mg/mL, clone AS32, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
neutralization
western blot
Monoclonal Anti-CTLA4 antibody produced in mouse, clone 2F1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-CD152 (CTLA-4) (mouse), PE-Cy7, clone UC10-4F10-11 Antibody, clone UC10-4F10-11, from hamster(Armenian), PE-Cy7,
物种反应性
mouse
应用
flow cytometry

Proteins

货号
说明
物种
CD152(人):FC(人)(非分解), recombinant, expressed in CHO cells, ≥98% (SDS-PAGE),
物种
human
CD152/Fc Chimera, Cytolytic from mouse, recombinant, expressed in NS.1 cells, buffered aqueous solution,
物种
mouse

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CTLA4,
物种
human