COL6A3
collagen, type VI, alpha 3
别名:
物种:
Human COL6A3 (1293), Mouse Col6a3 (12835), Rat Col6a3 (367313), dog COL6A3 (403582), chicken COL6A3 (396548), domestic guinea pig Col6a3 (100716662), cow COL6A3 (530657), naked mole-rat Col6a3 (101717072), Zebrafish col6a3 (556874), domestic cat COL6A3 (101081323)
UniProtKB ID:
基因ID:
- Human(1293) Summary: This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009]
- Mouse(12835) collagen, type VI, alpha 3
- Rat(367313) collagen, type VI, alpha 3
- dog(403582) collagen, type VI, alpha 3
- chicken(396548) collagen, type VI, alpha 3
- domestic guinea pig(100716662) collagen, type VI, alpha 3
- cow(530657) collagen, type VI, alpha 3
- naked mole-rat(101717072) collagen, type VI, alpha 3
- Zebrafish(556874) collagen, type VI, alpha 3
- domestic cat(101081323) collagen, type VI, alpha 3
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Antibodies
货号
说明
物种反应性
应用
抗VI型胶原抗体，克隆3C4, ascites fluid, clone 3C4, Chemicon®,
物种反应性
human
应用
electron microscopy
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
抗-COL6A3 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-Collagen VI alpha-3 Antibody, clone 3C4, Ascites Free, culture supernatant, clone 3C4, from mouse,
物种反应性
human
应用
electron microscopy
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
Anti-Collagen VI α3 Antibody, clone 1D6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Collagen VI α3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry