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Merck
CN

CISH

cytokine inducible SH2-containing protein

别名:
BACTS2, CIS, CIS-1, G18, SOCS
物种:
UniProtKB ID:
基因ID:
  • Human(1154) Summary: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(12700) cytokine inducible SH2-containing protein
  • Rat(83681) cytokine inducible SH2-containing protein
  • dog(484757) cytokine inducible SH2-containing protein
  • domestic cat(101096550) cytokine inducible SH2-containing protein
  • chicken(395335) cytokine inducible SH2-containing protein
  • naked mole-rat(101716746) cytokine inducible SH2-containing protein
  • cow(616753) cytokine inducible SH2-containing protein
  • domestic guinea pig(100719354) cytokine inducible SH2-containing protein
  • Zebrafish(767678) cytokine inducible SH2-containing protein
  • sheep(101119259) cytokine inducible SH2-containing protein

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Antibodies

货号
说明
物种反应性
应用
Anti-CISH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-CISH antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-CISH antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CISH,
物种
human
MISSION® esiRNA, targeting mouse Cish,
物种
mouse