跳转至内容
Merck
CN

CHN2

chimerin 2

别名:
ARHGAP3, BCH, CHN2-3, RHOGAP3
物种:
UniProtKB ID:
基因ID:
  • Human(1124) Summary: This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(69993) chimerin (chimaerin) 2
  • Rat(84031) chimerin 2
  • domestic cat(101093762) chimerin 2
  • Domestic Rabbit(100344407) chimerin 2
  • dog(475267) chimerin 2
  • Zebrafish(570999) chimerin (chimaerin) 2
  • domestic guinea pig(100723720) chimerin 2
  • naked mole-rat(101701673) chimerin 2
  • chicken(428437) chimerin (chimaerin) 2
  • cow(507285) chimerin (chimaerin) 2
  • sheep(101103716) chimerin 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-CHN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-CHN2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, horse, human, mouse, rabbit, rat
应用
western blot
Anti-CHN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting human CHN2,
物种
human
MISSION® esiRNA, targeting human CHN2 (2),
物种
human
MISSION® esiRNA, targeting mouse Chn2,
物种
mouse