跳转至内容
Merck
CN

CD8B

CD8b molecule

别名:
CD8B1, LEU2, LY3, LYT3, P37
物种:
UniProtKB ID:
基因ID:
  • Human(926) Summary: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
  • Rat(24931) CD8b molecule
  • domestic guinea pig(100379572) CD8b molecule
  • naked mole-rat(101720046) CD8b molecule
  • chicken(396175) CD8b molecule
  • sheep(101103712) CD8b molecule
  • dog(483076) CD8b molecule
  • domestic cat(493948) CD8b molecule
  • cow(508633) CD8b molecule

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-CD8B1 antibody produced in mouse, clone 4C8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-CD8B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-CD8B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-CD8B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Monoclonal Anti-CD8 antibody produced in mouse, clone UCHT-4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CD8B,
物种
human