CD1E
CD1e molecule
别名:
CD1A, R2
物种:
Human CD1E (913), domestic guinea pig Cd1e (100379271), cow CD1E (510832), Domestic Rabbit CD1E (100008782), dog CD1E (488610), domestic cat CD1E (101098516)
UniProtKB ID:
基因ID:
- Human(913) Summary: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010]
- domestic guinea pig(100379271) CD1e molecule
- cow(510832) CD1e molecule
- Domestic Rabbit(100008782) CD1e molecule
- dog(488610) CD1e molecule
- domestic cat(101098516) CD1e molecule
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Antibodies
货号
说明
物种反应性
应用
Anti-Cd1E Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-CD1E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
esiRNA
货号
说明
物种