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Merck
CN

CCR3

chemokine (C-C motif) receptor 3

别名:
CC-CKR-3, CD193, CKR3, CMKBR3
物种:
UniProtKB ID:
基因ID:
  • Human(1232) Summary: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
  • Mouse(12771) chemokine (C-C motif) receptor 3
  • Rat(117027) chemokine (C-C motif) receptor 3
  • domestic guinea pig(100135496) chemokine (C-C motif) receptor 3
  • domestic guinea pig(100718618) chemokine (C-C motif) receptor 3
  • naked mole-rat(101724462) chemokine (C-C motif) receptor 3
  • cow(408018) chemokine (C-C motif) receptor 3
  • sheep(443111) chemokine (C-C motif) receptor 3
  • domestic cat(100191005) chemokine (C-C motif) receptor 3
  • Thale Cress(824761) CRINKLY4 related 3
  • dog(448802) chemokine (C-C motif) receptor 3
  • Domestic Rabbit(100189557) chemokine (C-C motif) receptor 3

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Antibodies

货号
说明
物种反应性
应用
Anti-CCR3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CCR3 antibody produced in rabbit, affinity purified immunoglobulin (IgG),
物种反应性
应用
western blot
Anti-CCR3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-CD193 antibody produced in mouse, clone 5E8,
物种反应性
human
应用
flow cytometry
Monoclonal Anti-CD193-APC antibody produced in mouse, clone 5E8,
物种反应性
应用
flow cytometry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CCR3,
物种
human