BRAF
v-raf murine sarcoma viral oncogene homolog B
别名:
B-RAF1, BRAF1, NS7, RAFB1
物种:
Human BRAF (673), Mouse Braf (109880), Rat Braf (114486), Horse BRAF (100065760), Zebrafish braf (403065), naked mole-rat Braf (101702762), chicken BRAF (396239), domestic guinea pig Braf (100717765), dog BRAF (475526), domestic cat BRAF (101092346) ...展开
UniProtKB ID:
基因ID:
- Human(673) Summary: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109880) Braf transforming gene
- Rat(114486) v-raf murine sarcoma viral oncogene homolog B
- Horse(100065760) v-raf murine sarcoma viral oncogene homolog B1
- Zebrafish(403065) v-raf murine sarcoma viral oncogene homolog B1
- naked mole-rat(101702762) v-raf murine sarcoma viral oncogene homolog B1
- chicken(396239) v-raf murine sarcoma viral oncogene homolog B1
- domestic guinea pig(100717765) v-raf murine sarcoma viral oncogene homolog B1
- dog(475526) v-raf murine sarcoma viral oncogene homolog B1
- domestic cat(101092346) v-raf murine sarcoma viral oncogene homolog B1
- cow(536051) v-raf murine sarcoma viral oncogene homolog B
- sheep(101107438) v-raf murine sarcoma viral oncogene homolog B1
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Antibodies
货号
说明
物种反应性
应用
兔抗BRAF (V600E)单克隆抗体, recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin,
物种反应性
human
应用
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-BRAF (V600E) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Anti-BRAF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Anti-BRAF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-B-Raf Antibody, clone 2D3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
avian, bovine, feline, fish, human, monkey, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Cell Lines
货号
说明
物种
Proteins
货号
说明
物种
BRAF (416-766), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human