BEST1
bestrophin 1
别名:
ARB, BEST, BMD, RP50, TU15B, VMD2
物种:
Human BEST1 (7439), Mouse Best1 (24115), Rat Best1 (293735), domestic cat BEST1 (101084904), domestic guinea pig Best1 (100723621), naked mole-rat Best1 (101710606), dog BEST1 (483791), cow BEST1 (508924), sheep BEST1 (101109837), fruit fly Best1 (53431) ...展开
UniProtKB ID:
基因ID:
- Human(7439) Summary: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
- Mouse(24115) bestrophin 1
- Rat(293735) bestrophin 1
- domestic cat(101084904) bestrophin 1
- domestic guinea pig(100723621) bestrophin 1
- naked mole-rat(101710606) bestrophin 1
- dog(483791) bestrophin 1
- cow(508924) bestrophin 1
- sheep(101109837) bestrophin 1
- fruit fly(53431) Bestrophin 1
- Domestic Rabbit(100352203) bestrophin 1
- Horse(100059901) bestrophin 1
- chicken(423124) bestrophin 1
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Antibodies
货号
说明
物种反应性
应用
Anti-Bestrophin Antibody, Chemicon®, from mouse,
物种反应性
bovine, human, monkey, mouse, pig
应用
immunohistochemistry
western blot
western blot
Anti-BEST1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-VMD2 antibody produced in mouse, clone 1C2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot