ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
别名:
GBD4, STSL
物种:
Human ABCG8 (64241), Mouse Abcg8 (67470), Rat Abcg8 (155192), Zebrafish abcg8 (100136850), chicken ABCG8 (421402), dog ABCG8 (474571), Horse ABCG8 (100069071), domestic cat ABCG8 (101099288), cow ABCG8 (508829), Domestic Rabbit ABCG8 (100350554) ...展开
UniProtKB ID:
基因ID:
- Human(64241) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
- Mouse(67470) ATP-binding cassette, sub-family G (WHITE), member 8
- Rat(155192) ATP-binding cassette, subfamily G (WHITE), member 8
- Zebrafish(100136850) ATP-binding cassette, sub-family G (WHITE), member 8
- chicken(421402) ATP-binding cassette, sub-family G (WHITE), member 8
- dog(474571) ATP-binding cassette, sub-family G (WHITE), member 8
- Horse(100069071) ATP-binding cassette, sub-family G (WHITE), member 8
- domestic cat(101099288) ATP-binding cassette, sub-family G (WHITE), member 8
- cow(508829) ATP-binding cassette, sub-family G (WHITE), member 8
- Domestic Rabbit(100350554) ATP-binding cassette, sub-family G (WHITE), member 8
- sheep(101113666) ATP-binding cassette, sub-family G (WHITE), member 8
- naked mole-rat(101723060) ATP-binding cassette, sub-family G (WHITE), member 8
- domestic guinea pig(100725586) ATP-binding cassette, sub-family G (WHITE), member 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-ABCG8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-ABCG8 Antibody, clone 1B10A5, clone 1B10A5, from mouse,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
esiRNA
货号
说明
物种