GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.

GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.

Reproduction (Cambridge, England) (2017-09-16)

Tomoyuki Muroi, Yuri Matsushima, Ryota Kanamori, Hikari Inoue, Wataru Fujii, Keiichiro Yogo

摘要

G-protein-coupled receptors (GPCRs) participate in diverse physiological functions and are promising targets for drug discovery. However, there are still over 140 orphan GPCRs whose functions remain to be elucidated.

材料

货号

品牌

产品描述

D5796

Sigma-Aldrich

杜氏改良 Eagle 培养基 - 高葡萄糖, With 4500 mg/L glucose, L-glutamine, and sodium bicarbonate, without sodium pyruvate, liquid, sterile-filtered, suitable for cell culture

A5955

Sigma-Aldrich

抗生素抗霉菌溶液（100×），稳定, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture