Exploration of acute genotoxic effects and antigenotoxic potential of gambogic acid using Allium cepa assay.

Exploration of acute genotoxic effects and antigenotoxic potential of gambogic acid using Allium cepa assay.

Plant physiology and biochemistry : PPB (2017-08-15)

Abhishek Shetty, Thejaswini Venkatesh, Padmanaban S Suresh, Rie Tsutsumi

摘要

The plant derived xanthanoid gambogic acid (GA) is well known for its anticancer activity. To date, biological actions of GA on plant system have not been reported. In the present study, we evaluated the potential acute genotoxic activity of GA, and its antigenotoxic potential against H