- Online monitoring of hepatic rat metabolism by coupling a liver biochip and a mass spectrometer.
Online monitoring of hepatic rat metabolism by coupling a liver biochip and a mass spectrometer.
The Analyst (2017-09-12)
Franck Merlier, Rachid Jellali, Eric Leclerc
PMID28891561
摘要
A microfluidic liver biochip was coupled with a mass spectrometer to detect in real time the drug metabolism of hepatocytes. The hepatocytes were cultivated in the biochip for 35 h. The biochip was placed in a small-scale incubator in which the temperature and CO