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  • Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.

Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine.

EBioMedicine (2017-09-01)
Elisabeth Thulin, Måns Thulin, Dan I Andersson
PMID28855073
摘要

Mecillinam (amdinocillin) is a β-lactam antibiotic used to treat uncomplicated urinary tract infections (UTIs). We have previously shown that inactivation of the Escherichia coli cysB gene is the major cause of mecillinam resistance (Mec