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  • ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca

ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca

International journal of biological sciences (2017-11-07)
Yang Long, Ji-Yi Xia, Shao-Wei Chen, Chen-Lin Gao, Guan-Nan Liang, Xue-Mei He, Jian Wu, Chun-Xia Jiang, Xin Liu, Wei Huang, Qin Wan, Yong Xu
摘要

Endothelial cell insulin resistance may be partially responsible for the higher risk of atherosclerosis and cardiovascular disease in populations with insulin resistance and type 2 diabetes mellitus (T2DM). A genome-wide association study revealed a significant association between the ATPase plasma membrane Ca

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MISSION® esiRNA, targeting human ATP2B1