Subsistence of inclusion complex via assembly of a drug into cyclic oligosaccharide: Its formation, mechanism, behaviour and importance.

The aim of this present work is to make soluble DEPM in aqueous medium through the formation inclusion complex into the hydrophobic hollow space of β-cyclodextrin (β-Cyd) which will provide a novel approach for designing drug delivery system in aqueous medium. The study of supramolecular complexation of DEPM with β-Cyd has been designed in both solution and solid state. In solution phase the evidences of the presence of non-covalent interactions in inclusion complex with 1:1 stoichiometry behaviour are obtained by investigating the UV-spectroscopy. The resultant solid of DEPM and β-Cyd is established by