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Cobalt: its role in health and disease.

Cobalt: its role in health and disease.

Metal ions in life sciences (2014-01-29)

Kazuhiro Yamada

摘要

The primarily function of cobalt in humans is based on its role in cobalamin (Cbl, vitamin B12). Therefore, this chapter will focus on the physiological roles of Cbl and the importance of cobalt in human health. Cbl acts as the cofactor for two enzymes, i.e., methylmalonyl-CoA mutase and methionine synthase, in humans. Both enzymes are important for health. In addition, unlike other water-soluble vitamins, there is a unique absorption, delivery, and activation system for Cbl in mammals. Therefore, this chapter will also review the literature on the Cbl transporting system, which is crucial for Cbl function.

材料

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产品描述

Sigma-Aldrich

钴, powder, 2 μm particle size, 99.8% trace metals basis

Sigma-Aldrich

钴, granular, 99.99% trace metals basis

Sigma-Aldrich

钴, Carbon coated magnetic, nanopowder, <50 nm particle size (TEM), ≥99%

Sigma-Aldrich

钴, pieces, 99.5% trace metals basis

Sigma-Aldrich

钴, foil, thickness 0.1 mm, 99.95% trace metals basis

Sigma-Aldrich

钴, rod, diam. 5.0 mm, 99.95% trace metals basis

Sigma-Aldrich

钴, wire, diam. 1.0 mm, 99.995% trace metals basis

钴, foil, 100x100mm, thickness 2.0mm, as rolled, 99.9%

钴, foil, 100x100mm, thickness 1.0mm, as rolled, 99.9%

Sigma-Aldrich

钴, foil, thickness 1.0 mm, 99.95% trace metals basis

钴, foil, light tested, 25x25mm, thickness 0.01mm, 99.9%

Sigma-Aldrich

钴, foil, thickness 0.1 mm, ≥99.99%

钴, wire reel, 0.5m, diameter 0.05mm, hard, 99.9%

钴, foil, 100x100mm, thickness 0.25mm, as rolled, 99.9%

钴, foil, light tested, 25x25mm, thickness 0.0125mm, 99.9%

钴, foil, light tested, 25x25mm, thickness 0.05mm, as rolled, 99.9%

钴, microfoil, disks, 10mm, thinness 0.5μm, specific density 434μg/cm², permanent mylar 3.5μm support, 99.9%

钴, microfoil, disks, 25mm, thinness 0.25μm, specific density 222μg/cm², permanent mylar 3.5μm support, 99.9%

钴, wire reel, 0.1m, diameter 0.05mm, hard, 99.9%

钴, foil, light tested, 25x25mm, thickness 0.015mm, 99.9%

钴, foil, light tested, 25x25mm, thickness 0.025mm, 99.9%

钴, foil, not light tested, 25x25mm, thickness 0.01mm, 99.9%

钴, wire reel, 0.05m, diameter 0.25mm, hard, 99.99+%

钴, foil, not light tested, 100x100mm, thickness 0.02mm, 99.9%

钴, wire reel, 0.1m, diameter 0.5mm, hard, 99.99+%

钴, foil, light tested, 25x25mm, thickness 0.009mm, 99.9%

钴, foil, light tested, 50x50mm, thickness 0.0125mm, 99.9%

钴, foil, light tested, 50x50mm, thickness 0.05mm, as rolled, 99.99+%

钴, foil, not light tested, 25x25mm, thickness 0.003mm, 99.9%

钴, foil, not light tested, 25x25mm, thickness 0.005mm, 99.9%