Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2012-11-03)

Arlene C Seña, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H Martin, Peter Leone, Linda McNeil, Edward W Hook

摘要

Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.