- Serum protein binding of desmethyl-methsuximide.
Serum protein binding of desmethyl-methsuximide.
Clinical neuropharmacology (1999-08-12)
N Wad, B Bourgeois, G Krämer
PMID10442255
摘要
Serum protein binding of desmethyl-methsuximide (DM-MSM) in serum from 23 patients on polytherapy were determined using ultrafiltration and high-performance liquid chromatography. Desmethyl-methsuximide, The active metabolite of methsuximide (MSM), was found to have a moderate protein binding ranging between 45% and 60%.