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Merck
CN
  • Use of the loop diuretic torsemide in three dogs with advanced heart failure.

Use of the loop diuretic torsemide in three dogs with advanced heart failure.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology (2011-10-28)
Mark A Oyama, Gordon D Peddle, Caryn A Reynolds, Gretchen E Singletary
摘要

Diuretics are a mainstay of therapy in dogs with heart failure. In dogs with advanced heart failure, moderate to high doses of loop diuretics such as furosemide are used with diminishing effects as profound activation of neuroendocrine systems promote signs of congestive heart failure. The loop diuretic torsemide has several characteristics that make it suitable for treatment of advanced heart failure including longer half-life, increased potency of diuretic action, and anti-aldosterone effects. This case report details the administration of torsemide in 3 dogs with advanced heart failure and apparent furosemide resistance.

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Sigma-Aldrich
Torsemide, ≥98% (HPLC), solid