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  • Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole.

Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole.

Antimicrobial agents and chemotherapy (2011-07-13)
Betty Wächtler, Duncan Wilson, Bernhard Hube
摘要

Clotrimazole and bifonazole are highly effective antifungal agents against mucosal Candida albicans infections. Here we examined the effects of low levels of clotrimazole and bifonazole on the ability of C. albicans to adhere, invade, and damage vaginal epithelial cells. Although adhesion and invasion were not affected, damage was greatly reduced upon azole treatment. This clearly indicates that low levels of azoles influence specific activities of C. albicans during distinct stages of vaginal epithelium infections.

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Sigma-Aldrich
联苯苄唑, ≥98% (HPLC)
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Supelco
联苯苄唑, Pharmaceutical Secondary Standard; Certified Reference Material
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联苯苄唑, European Pharmacopoeia (EP) Reference Standard
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