- Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine.
Genotoxicity screening for N-nitroso compounds. Electrochemical and electrochemiluminescent detection of human enzyme-generated DNA damage from N-nitrosopyrrolidine.
Chemical communications (Cambridge, England) (2007-04-26)
Sadagopan Krishnan, Eli G Hvastkovs, Besnik Bajrami, Ingela Jansson, John B Schenkman, James F Rusling
PMID17457417
摘要
We report for the first time voltammetric/electrochemiluminescent sensors applied to predict genotoxicity of N-nitroso compounds bioactivated by human cytochrome P450 enzymes.