跳转至内容
Merck
CN
  • Synthesis and properties of cordycepin intercalates of Mg-Al-nitrate layered double hydroxides.

Synthesis and properties of cordycepin intercalates of Mg-Al-nitrate layered double hydroxides.

International journal of pharmaceutics (2006-08-08)
Qin Zheng Yang, Jing Yang, Chang Kai Zhang
摘要

Layered double hydroxides (LDHs) were investigated as cordycepin delivery nanocarriers for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO(3)] as the charge-compensating species, which was confirmed by the results of XRD, FT-IR, TEM, CZE and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.

材料
货号
品牌
产品描述

Sigma-Aldrich
硝酸铝 九水合物, ACS reagent, ≥98%
Sigma-Aldrich
硝酸铝 九水合物, 99.997% trace metals basis