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Merck
CN

Concise asymmetric total synthesis of obolactone.

The Journal of organic chemistry (2006-03-25)
Jiyong Zhang, Yang Li, Wenkuan Wang, Xuegong She, Xinfu Pan
摘要

The first efficient asymmetric synthesis of obolactone 1 has been accomplished in 11 steps and with a 15% overall yield in which Brown's enantioselective allylation reactions and ring-closing metathesis reaction are key steps.

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Sigma-Aldrich
4-苯基-3-丁烯-2-酮, 99%
Sigma-Aldrich
亚苄基丙酮, ≥98%, FG
Sigma-Aldrich
反式-4-苯基-3-丁烯-2-酮, ≥99%