[Effect of S-bioallethrin on human lymphocyte].

To study the effect of the S-bioallethrin on human lymphocytes by microarray technique. The changes of normal human lymphocytes treated with S-bioallethrin were examined with light microscope, flow cytometry, electron microscope, DNA ladder and microarray techniques. Morphological study showed that the lymphocytes underwent apoptosis after S-bioallethrin exposure, which as further confirmed by the expression changes of 346 genes. S-bioallethrin can induce apoptosis of normal human lymphocytes and changes in their gene expression profiles.