Synthetic studies of roquefortine C: synthesis of isoroquefortine C and a heterocycle.

Synthetic studies of roquefortine C: synthesis of isoroquefortine C and a heterocycle.

Proceedings of the National Academy of Sciences of the United States of America (2004-05-14)

David J Richard, Bruno Schiavi, Madeleine M Joullié

摘要

The syntheses of isoroquefortine C and a related heterocycle were achieved by implementation of both intra- and intermolecular vinyl amidation reactions. These accomplishments represent a significant advance in the use of these strategies in the generation of complex molecules.