Interferon and cell division. I. Inhibition of the multiplication of mouse leukemia L 1210 cells in vitro by interferon preparations.

Mouse interferon preparations inhibited the multiplication of mouse leukemia L 1210 cells in stationary suspension cultures. The degree of inhibition was found to correlate with the antiviral titer of the interferon preparations. The factor(s) responsible for inhibition of L 1210 cell multiplication could not be dissociated from interferon by standard physicochemical means.