Syntheses of S-enantiomers of hanishin, longamide B, and longamide B methyl ester from L-aspartic acid beta-methyl ester: establishment of absolute stereochemistry.

Syntheses of S-enantiomers of hanishin, longamide B, and longamide B methyl ester from L-aspartic acid beta-methyl ester: establishment of absolute stereochemistry.

The Journal of organic chemistry (2005-10-22)

Jignesh Patel, Nadia Pelloux-Léon, Frédéric Minassian, Yannick Vallée

摘要

[reaction: see text] Total syntheses of enantiopure hanishin, longamide B, and longamide B methyl ester are described. Absolute configurations of these natural products have been established.