- In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.
In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.
Antimicrobial agents and chemotherapy (2007-04-25)
Nikolaos G Almyroudis, Deanna A Sutton, Annette W Fothergill, Michael G Rinaldi, Shimon Kusne
PMID17452481
摘要
We evaluated the in vitro susceptibilities of 217 zygomycetes to amphotericin B, ketoconazole, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and flucytosine. The significant in vitro activity of posaconazole against several species appears to support its reported clinical efficacy. Decreased susceptibility to amphotericin B was noted with Cunninghamella bertholletiae.