P9417
棕榈油酸
≥98.5% (GC), liquid
别名:
顺式-9-棕榈油酸, 顺-9-十六烯酸
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关于此项目
线性分子式:
CH3(CH2)5CH=CH(CH2)7COOH
化学文摘社编号:
分子量:
254.41
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
206-765-9
Beilstein/REAXYS Number:
1725389
MDL number:
产品名称
棕榈油酸, ≥98.5% (GC), liquid
InChI
1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7-
InChI key
SECPZKHBENQXJG-FPLPWBNLSA-N
SMILES string
CCCCCC\C=C/CCCCCCCC(O)=O
biological source
Macadamia integrifolia
assay
≥98.5% (GC)
form
liquid
refractive index
n20/D 1.457 (lit.)
bp
162 °C/0.6 mmHg (lit.)
mp
0.5 °C (lit.)
density
0.895 g/mL at 20 °C (lit.)
functional group
carboxylic acid
oleic acid
lipid type
unsaturated FAs
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
棕榈油酸已用于：
- 补充最低必需培养基 alpha (MEM)，培养小鼠精原干细胞 (SSC)
- 用作指定成分无血清培养基成分，用于SSC长期繁殖
- 杜氏改良Eagle培养基(DMEM)的脂肪酸处理培养基，确保结合和未结合游离脂肪酸(FFA)维持生理比例
Biochem/physiol Actions
棕榈油酸是一种16碳，ω-7单不饱和脂肪酸，富含于人体脂肪组织和肝脏中的甘油三酯中。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
143.6 °F - closed cup
flash_point_c
62 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Yuko Akazawa et al.
Journal of hepatology, 52(4), 586-593 (2010-03-09)
Saturated free fatty acids induce hepatocyte lipoapoptosis. This lipotoxicity involves an endoplasmic reticulum stress response, activation of JNK, and altered expression and function of Bcl-2 proteins. The mono-unsaturated free fatty acid palmitoleate is an adipose-derived lipokine which suppresses free fatty
Dariush Mozaffarian et al.
The American journal of clinical nutrition, 97(4), 854-861 (2013-02-15)
Dairy consumption is linked to a lower risk of type 2 diabetes, but constituents responsible for this relation are not established. Emerging evidence suggests that trans-palmitoleate (trans 16:1n-7), a fatty acid in dairy and also partially hydrogenated oils, may be
Geng Zong et al.
The American journal of clinical nutrition, 96(5), 970-976 (2012-09-28)
Palmitoleic acid has been shown to regulate adipokine expression and systemic metabolic homeostasis in animal studies. However, its association with human metabolic diseases remains controversial. We aimed to investigate associations of erythrocyte palmitoleic acid with adipokines, inflammatory markers, and metabolic
Tahira Fatima et al.
PloS one, 7(4), e34099-e34099 (2012-05-05)
Sea buckthorn (Hippophae rhamnoides L.) is a hardy, fruit-producing plant known historically for its medicinal and nutraceutical properties. The most recognized product of sea buckthorn is its fruit oil, composed of seed oil that is rich in essential fatty acids
Katherine E Pinnick et al.
Diabetes, 61(6), 1399-1403 (2012-04-12)
The expansion of lower-body adipose tissue (AT) is paradoxically associated with reduced cardiovascular disease and diabetes risk. We examined whether the beneficial metabolic properties of lower-body AT are related to the production and release of the insulin-sensitizing lipokine palmitoleate (16:1n-7).
商品
Lipid Induced Insulin Resistance
脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入，并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。
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