如需咨询该产品HPA005985，请联系默克当地办事处或经销商。 联系客户支持
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
产品线
Prestige Antibodies® Powered by Atlas Antibodies
表单
buffered aqueous glycerol solution
种属反应性
human
技术
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:20-1:50
免疫原序列
RSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTA
1 of 4
此商品 | GF54847255 | GF41005718 | GF59528043 |
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| density 8.57 g/mL at 25 °C (lit.) | density 8.57 g/mL at 25 °C (lit.) | density 8.57 g/mL at 25 °C (lit.) | density 8.57 g/mL at 25 °C (lit.) |
| resistivity 13-16 μΩ-cm, 20°C | resistivity 13-16 μΩ-cm, 20°C | resistivity 13-16 μΩ-cm, 20°C | resistivity 13-16 μΩ-cm, 20°C |
| bp 4742 °C (lit.) | bp 4742 °C (lit.) | bp 4742 °C (lit.) | bp 4742 °C (lit.) |
| mp 2468 °C (lit.) | mp 2468 °C (lit.) | mp 2468 °C (lit.) | mp 2468 °C (lit.) |
免疫原
ribosomal protein S13 recombinant protein epitope signature tag (PrEST)
应用
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.
生化/生理作用
40S ribosomal protein S13 is a protein encoded by the RPS13 gene in humans. It is a structural element of the small subunit of ribosome and is a homologue of eubacterial ribosomal protein S15 and it possesses an extended N-terminal region. It is expressed at a higher level in gastric cancer tissues than that in normal gastric mucosa. Its overexpression could protect gastric cancer cells from drug-induced apoptosis. This gene may promote the growth and cell cycle progression of gastric cancer cells by inhibiting p27(kip1) expression.
特点和优势
Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.
Every Prestige Antibody is tested in the following ways:
Every Prestige Antibody is tested in the following ways:
- IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
- Protein array of 364 human recombinant protein fragments.
联系
Corresponding Antigen APREST86597
外形
Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.
法律信息
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
A V Ivanov et al.
Molekuliarnaia biologiia, 45(6), 1046-1054 (2012-02-03)
Human ribosomal protein S13 is a structural element of the small subunit of ribosome. It is a homologue of eubacterial ribosomal protein S15, and, besides, it possesses an extended N-terminal region, characteristic of the S15p family in eukaryotes and archaea.
Xueyan Guo et al.
Journal of cellular and molecular medicine, 15(2), 296-306 (2009-11-17)
Our previous works revealed that human ribosomal protein S13 (RPS13) was up-regulated in multidrug-resistant gastric cancer cells and overexpression of RPS13 could protect gastric cancer cells from drug-induced apoptosis. The present study was designed to explore the role of RPS13
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持
