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Merck
CN

H2012

己酰基辅酶A 三锂盐 水合物

≥85%

别名:

己酰基辅酶A 三锂盐

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关于此项目

经验公式(希尔记法):
C27H43Li3N7O17P3S · xH2O
化学文摘社编号:
分子量:
883.48 (anhydrous basis)
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Assay:
≥85%
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Quality Level

assay

≥85%

storage temp.

−20°C

SMILES string

[Li+].[Li+].[Li+].O.CCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23

InChI

1S/C27H46N7O17P3S.3Li.H2O/c1-4-5-6-7-18(36)55-11-10-29-17(35)8-9-30-25(39)22(38)27(2,3)13-48-54(45,46)51-53(43,44)47-12-16-21(50-52(40,41)42)20(37)26(49-16)34-15-33-19-23(28)31-14-32-24(19)34;;;;/h14-16,20-22,26,37-38H,4-13H2,1-3H3,(H,29,35)(H,30,39)(H,43,44)(H,45,46)(H2,28,31,32)(H2,40,41,42);;;;1H2/q;3*+1;/p-3/t16-,20-,21-,22+,26-;;;;/m1..../s1

InChI key

YMMJFYLVSRICJX-ZTADYLHKSA-K

Application

已酰辅酶 A 三锂盐水合物可用作液相色谱-串联质谱法 (LC-MS/MS) 的标准品。

Biochem/physiol Actions

辅酶 A 作为酰基载体,乙酰辅酶 A 发挥作用。己酰基 CoA 参与脂肪酸氧化、脂质生物合成和神经酰胺形成。胃饥饿素 O-酰基转移酶 (GOAT) 对 n-己酰基辅酶 a 的偏好超过 n-辛酰辅酶 a 作为酰基供体。已酰 CoA 也用作聚酮生物合成的起始单元。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

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Nobutaka Funa et al.
The Biochemical journal, 367(Pt 3), 781-789 (2002-07-26)
RppA, which belongs to the type III polyketide synthase family, catalyses the synthesis of 1,3,6,8-tetrahydroxynaphthalene (THN), which is the key intermediate of melanin biosynthesis in the bacterium Streptomyces griseus. The reaction of THN synthesis catalysed by RppA is unique in
LC-MS/MS-based analysis of coenzyme A and short-chain acyl-coenzyme A thioesters
Neubauer S, et al.
Analytical and Bioanalytical Chemistry, 407(22), 6681-6688 (2015)
Miao He et al.
The Journal of biological chemistry, 278(39), 37974-37986 (2003-07-12)
Rat and human short/branched chain acyl-CoA dehydrogenases exhibit key differences in substrate specificity despite an overall amino acid identity of 85% between them. Rat short/branched chain acyl-CoA dehydrogenases (SBCAD) are more active toward substrates with longer carbon side chains than



全球贸易项目编号

货号GTIN
H2012-10MG04061833262238
H2012-5MG04061833262245