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Merck
CN

H1635

马尿酰-组氨酰-亮氨酸 水合物

chromogenic, ≥98% (HPLC), powder

别名:

N-Benzoyl-Gly-His-Leu, N-马尿酰-L-组氨酰-L-亮氨酸 水合物

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关于此项目

经验公式(希尔记法):
C21H27N5O5 · xH2O
化学文摘社编号:
分子量:
429.47 (anhydrous basis)
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
250-597-9
MDL number:
Beilstein/REAXYS Number:
5664178
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产品名称

马尿酰-组氨酰-亮氨酸 水合物, powder, ≥98% (HPLC)

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

acetic acid: ~50 mg/mL

storage temp.

−20°C

SMILES string

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1

InChI key

NWOJMNXIJBZMPK-QJHJCNPRSA-N

Gene Information

General description

血管紧张素转换酶底物。

Application

N-马尿酰组氨酰亮氨酸水合物可用于对牡蛎水解产物、半膜肌样品和兔肺丙酮粉末进行血管紧张素转换酶(ACE)的抑制性检测。

Biochem/physiol Actions

N-马尿酰组氨酰亮氨酸水合物(HHL)可用作血管紧张素转换酶(ACE)的人造底物。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
In Silico Elucidation of the Molecular Recognition of Phenol Derivative Compounds and Hippuryl-histidyl-leucine as an Artificial Substrate with the Experimental Target: Angiotensin-converting Enzyme
Vazquez-Valaldez VH, et al.
Letters in Drug Design & Discovery (2020)
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged



全球贸易项目编号

货号GTIN
H1635-100MG04061835545438
H1635-500MG04061835512607
H1635-25MG04061835557080
H1635-1G04061833672686