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Merck
CN

A9731

白蛋白 人

Cellastim S, recombinant, expressed in rice, lyophilized powder, suitable for cell culture, low endotoxin, ≥96% (SDS-PAGE)

别名:

Cellastim S,rHSA, rHSA

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关于此项目

经验公式(希尔记法):
C2936H4624N786O889S41
化学文摘社编号:
分子量:
66471.53
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.25
MDL number:
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产品名称

白蛋白 人, Cellastim S, recombinant, expressed in rice, lyophilized powder, suitable for cell culture, low endotoxin, ≥96% (SDS-PAGE)

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

biological source

human

recombinant

expressed in rice

assay

≥96% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer ~67 kDa

technique(s)

cell culture | mammalian: suitable

impurities

≤1 EU/mg protein

UniProt accession no.

storage temp.

2-8°C

Quality Level

Gene Information

human ... ALB(213)

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Analysis Note

SDS-PAGE测定

Application

该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。

Biochem/physiol Actions

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

Features and Benefits

Cellastim是一种性质明确、无动物源成分的重组型人白蛋白(rHA)。 Cellastim专为细胞培养应用而设计,是一种性能优于血浆来源的人白蛋白、牛血清白蛋白和其他来源的重组人白蛋白的强大培养基补充剂。Cellastim带来的是稳定一致的性能,而不是与水解产物和提取物相关的变量。Cellastim是适用于中国仓鼠卵巢(CHO)、杂交瘤、VERO、干细胞和原代细胞培养基的理想选择。

优势
  • 消除了动物来源的添加剂
  • 安全且符合监管要求
  • 证明在胚胎、间充质、神经、心脏、肝脏、肾脏、角质形成细胞和成纤维干细胞系中可有效增强干细胞的生长
  • 维持干细胞处在未分化状态
  • 消除了贴壁细胞系培养板的涂层
  • 提供性质明确且稳定一致的干细胞培养基

Other Notes

1)。专利权
EP2230311
美国专利号10,618,951
美国专利号10,981,974
美国专利号11,492,3892。
2)。注册商标权
美国注册号5696531
国际注册号1456207
如需了解Cellastim的更多信息,可下载Cellastim手册Cellastim CHO海报以及Cellastim杂交瘤海报
更多信息参见人血清白蛋白

Legal Information

rHSA manufactured in the USA by InVitria US Pat 10618951, 10981974, and 11492389.
Cellastim is a trademark of InVitria

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
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分析证书(COA)

Lot/Batch Number

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D Moreno et al.
Theriogenology, 84(7), 1053-1060 (2015-08-19)
The aim of this study was to develop an in vitro embryo culture medium without either fetal calf serum or BSA, using various growth factors and cytokines (GFs-CYKs; IGF-I, IGF-II, bFGF, LIF, GM-CSF, TGF-β1, and PDGF-BB), and other molecules with
Yongjia Fan et al.
ACS biomaterials science & engineering, 3(8), 1510-1518 (2016-08-14)
The development of platforms for the expansion and directed differentiation of human pluripotent stem cells (hPSCs) in large quantities under xeno-free conditions is a key step toward the realization of envisioned stem cell-based therapies. Microcarrier bioreactors afford great surface-to-volume ratio
Junfeng Zhu et al.
Journal of pharmaceutical and biomedical analysis, 134, 100-107 (2016-11-28)
Danhong injection (DHI) is a widely used Chinese medicine injection (CMI) for the clinical treatment of cardiovascular and cerebrovascular diseases. In this study, a simple and efficient in vitro method based on ultrafiltration LC-MS and molecular modeling has been developed
Wireeya Chawjiraphan et al.
MethodsX, 7, 101114-101114 (2020-11-17)
A simple and sensitive graphene oxide-mediated fluorescence quenching aptasensor is developed to quantify albuminuria in urine samples. The developed aptasensor used the specific target binding property of aptamer and fluorescence quenching property of graphene oxide to determine the concentration of
Malte Tiburcy et al.
STAR protocols, 1(1), 100032-100032 (2020-10-29)
This protocol describes a robust method for the generation of engineered human myocardium (EHM) from pluripotent stem cells (PSCs) in a multi-well plate under defined, serum-free conditions. By parallel culture of up to 48 EHM in one plate, contractile heart

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本页将全面阐述血清白蛋白和其他重要细胞培养成分如何影响用于单克隆抗体等外源蛋白生物制造的无血清细胞培养系统的性能,并介绍白蛋白的体外化学和生物化学过程。本页面将介绍白蛋白在体外化学和生物化学领域的应用。这些深度知识可能也适用于离体和组织工程学应用。

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