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关于此项目
经验公式（希尔记法）:
C40H80NO8P
化学文摘社编号:
分子量:
734.04
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
14:0-18:0 PC, 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850446P-200mg), pkg of 1 × 25 mg (850446P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850446P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41(3,4)5)36-46-39(42)32-30-28-26-24-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChI key
TYAQXZHDAGZOEO-KXQOOQHDSA-N
General description
磷脂酰胆碱（PC）是结肠′粘膜层最重要的成分之一。14:0-18:0 PC（1-肉豆蔻酰基-2-硬脂酰基-sn-甘油-3-磷酸胆碱）是具有长烷基侧链的不对称脂质。
Application
14:0-18:0 PC（1-肉豆蔻酰基-2-硬脂酰基-sn-甘油-3-磷酸胆碱）可用于：
- 脂质双层，采用差示扫描量热法（DSC）研究其与d-赤型-N-棕榈酰基-鞘磷脂（16:0-SM）的混溶性，
- 作为脂质体中的不对称脂质成分，研究双层面积和脂质几何形状的影响，并作为脂质体增溶剂
- 制备用于溶栓研究的低温敏感脂质体
Biochem/physiol Actions
磷脂酰胆碱（PC）通过充当表面活性剂在粘液中形成疏水表面，从而抑制细菌的渗透。
Packaging
5 mL棕色玻璃螺旋盖小瓶（850446P-200mg）
5 mL棕色玻璃螺旋盖小瓶（850446P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Vishal Saxena et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 31(1), 67-73 (2015-03-15)
Clinical efficacy of thrombolytic drugs is limited by lack of specific delivery and requires large therapeutic doses which increase toxicity. Encapsulating these drugs in temperature-sensitive liposomes and applying hyperthermia to deliver thrombolytic agents locally to thrombus might theoretically favourably alter
M Habib Ali et al.
International journal of pharmaceutics, 453(1), 225-232 (2012-07-07)
Liposomes are well recognised for their ability to improve the delivery of a range of drugs. More commonly they are applied for the delivery of water-soluble drugs, but given their structural attributes, they can also be employed as solubilising agents
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 850446P-200MG | 04061835230808 |
| 850446P-25MG | 04061835230815 |