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850368C

Avanti

20:0 PC

Avanti Research™ - A Croda Brand

别名:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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关于此项目

经验公式（希尔记法）:
C48H96NO8P
化学文摘社编号:
61596-53-0
分子量:
846.25
MDL number:
MFCD00067533
UNSPSC Code:
51191904
NACRES:
NA.25
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产品名称

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850368C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850368C

concentration

10 mg/mL (850368C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

InChI key

YKIOPDIXYAUOFN-YACUFSJGSA-N

General description

The mucosal layer of the colon has phosphatidylcholine (PC) as a vital constituent.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

20:0 PC has been used in collision cross section (CCS) calibration mixture for lipid identification.
It may be used:
  • as a component in giant unilamellar vesicles (GUVs) for a two-photon fluorescence microscopy study
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization
  • as a component in giant unilamellar vesicles (GUVs) to study its interaction with Crotalus atrox-secreted phospholipase A2 (sPLA2)

Biochem/physiol Actions

Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation. It can serve as a surfactant to block the penetrance of bacteria by generating a hydrophobic surface.

Packaging

5 mL Clear Glass Sealed Ampule (850368C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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wgk

WGK 3

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

易制毒化学品（2类）
危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Susana A Sanchez et al.
Biophysical journal, 82(4), 2232-2243 (2002-03-28)
We describe the interaction of Crotalus atrox-secreted phospholipase A2 (sPLA2) with giant unilamellar vesicles (GUVs) composed of single and binary phospholipid mixtures visualized through two-photon excitation fluorescent microscopy. The GUV lipid compositions that we examined included 1-palmitoyl-2-oleoyl-phosphatidylcholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and
The Use of LipidIMMS Analyzer for Lipid Identification in Ion Mobility-Mass Spectrometry-Based Untargeted Lipidomics
Ion Mobility-Mass Spectrometry, 269-282 (2020)
L A Bagatolli et al.
Biophysical journal, 79(1), 434-447 (2000-06-27)
Giant unilamellar vesicles (GUVs) composed of different phospholipid binary mixtures were studied at different temperatures, by a method combining the sectioning capability of the two-photon excitation fluorescence microscope and the partition and spectral properties of 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan) and Lissamine rhodamine
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全球贸易项目编号

货号GTIN
850368C-25MG04061837792274