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关于此项目
经验公式（希尔记法）:
C39H76O8PNa
化学文摘社编号:
分子量:
726.98
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
description
1,2-distearoyl-sn-glycero-3-phosphate (sodium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (830865P-25mg), pkg of 1 × 500 mg (830865P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)O
InChI
1S/C39H77O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h37H,3-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/t37-;/m1./s1
InChI key
ALPWRKFXEOAUDR-GKEJWYBXSA-M
General description
磷脂酸（PA）具有两个脂肪酸和一个磷酸盐，连接到甘油主链的磷酸盐。这两种脂肪酸存在于C原子的sn-1和sn-2位置，磷酸盐基存在于C原子的sn-3位置。
Application
18:0 PA可用于：
- 作为双层膜的成分，研究其对不同外壳蛋白I（COPI）裂变因子的囊泡形成能力，
- 研究其对C6大鼠胶质瘤和L2071小鼠成纤维细胞内Ca2+浓度（[Ca2+]i）的影响
- 研究其对细胞色素b（558）α链（p22phox）磷酸化的影响
Biochem/physiol Actions
磷脂酸（PA）充当生产膜甘油磷脂和三酰基甘油的生物合成前体。它参与调节哺乳动物雷帕霉素靶蛋白（mTOR）途径。它也可能参与膜运输，特别是膜融合和裂变。
Packaging
20 mL透明玻璃螺旋盖小瓶（830865P-500mg）
5 mL棕色玻璃螺旋盖小瓶（830865P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Peter Bond
Nutrition & metabolism, 14, 12-12 (2017-02-12)
The mechanistic target of rapamycin complex 1 (mTORC1) has received much attention in the field of exercise physiology as a master regulator of skeletal muscle hypertrophy. The multiprotein complex is regulated by various signals such as growth factors, energy status
D S Regier et al.
The Journal of biological chemistry, 274(51), 36601-36608 (1999-12-14)
Using a phosphorylation-dependent cell-free system to study NADPH oxidase activation (McPhail, L. C., Qualliotine-Mann, D., and Waite, K. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7931-7935), we previously showed that p47(phox), a cytosolic NADPH oxidase component, is
Emeline Tanguy et al.
Frontiers in cellular neuroscience, 13, 2-2 (2019-02-08)
Among the cellular lipids, phosphatidic acid (PA) is a peculiar one as it is at the same time a key building block of phospholipid synthesis and a major lipid second messenger conveying signaling information. The latter is thought to largely
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 830865P-500MG | 04061835228478 |
| 830865P-25MG | 04061835228461 |