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Merck
CN

VAMP2

vesicle-associated membrane protein 2 (synaptobrevin 2)

别名:
SYB2, VAMP-2
物种:
UniProtKB ID:
基因ID:
  • Human(6844) Summary: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
  • Mouse(22318) vesicle-associated membrane protein 2
  • Rat(24803) vesicle-associated membrane protein 2
  • Zebrafish(336281) vesicle-associated membrane protein 2
  • domestic guinea pig(100732271) vesicle-associated membrane protein 2 (synaptobrevin 2)
  • naked mole-rat(101711585) vesicle-associated membrane protein 2 (synaptobrevin 2)
  • sheep(101122451) vesicle-associated membrane protein 2 (synaptobrevin 2)
  • domestic cat(101101516) vesicle-associated membrane protein 2 (synaptobrevin 2)
  • cow(282116) vesicle-associated membrane protein 2 (synaptobrevin 2)
  • chicken(424827) vesicle-associated membrane protein 2 (synaptobrevin 2)
  • dog(479491) vesicle-associated membrane protein 2 (synaptobrevin 2)

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Antibodies

货号
说明
物种反应性
应用
Anti-VAMP2 Antibody, clone 8X9D9, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunofluorescence
western blot
Anti-VAMP-2 Antibody, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human VAMP2,
物种
human