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Merck
CN

TNFRSF25

tumor necrosis factor receptor superfamily, member 25

别名:
APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR
物种:
UniProtKB ID:
基因ID:
  • Human(8718) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
  • Mouse(85030) tumor necrosis factor receptor superfamily, member 25
  • Rat(500592) tumor necrosis factor receptor superfamily, member 25
  • sheep(101116668) tumor necrosis factor receptor superfamily, member 25
  • cow(783432) tumor necrosis factor receptor superfamily, member 25
  • domestic guinea pig(100724303) tumor necrosis factor receptor superfamily, member 25
  • domestic cat(101090784) tumor necrosis factor receptor superfamily, member 25
  • chicken(425564) tumor necrosis factor receptor superfamily, member 25
  • dog(489632) tumor necrosis factor receptor superfamily, member 25
  • naked mole-rat(101703558) tumor necrosis factor receptor superfamily, member 25

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ELISA

货号
说明
物种
人DR3 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-DR3 antibody produced in mouse, clone JD3,
物种反应性
human
应用
flow cytometry
Monoclonal Anti-TNFRSF25 antibody produced in mouse, clone 1H2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Tnfrsf25,
物种
mouse