STAT2
signal transducer and activator of transcription 2, 113kDa
别名:
ISGF-3, P113, STAT113
物种:
Human STAT2 (6773), Mouse Stat2 (20847), Rat Stat2 (288774), dog STAT2 (481111), sheep STAT2 (101108211), cow STAT2 (511023), naked mole-rat Stat2 (101707295), domestic cat STAT2 (101099224), domestic guinea pig Stat2 (100719719), Zebrafish stat2 (565200)
UniProtKB ID:
基因ID:
- Human(6773) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
- Mouse(20847) signal transducer and activator of transcription 2
- Rat(288774) signal transducer and activator of transcription 2
- dog(481111) signal transducer and activator of transcription 2, 113kDa
- sheep(101108211) signal transducer and activator of transcription 2, 113kDa
- cow(511023) signal transducer and activator of transcription 2, 113kDa
- naked mole-rat(101707295) signal transducer and activator of transcription 2, 113kDa
- domestic cat(101099224) signal transducer and activator of transcription 2, 113kDa
- domestic guinea pig(100719719) signal transducer and activator of transcription 2, 113kDa
- Zebrafish(565200) signal transducer and activator of transcription 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-STAT2 Antibody, CT, Upstate®, from rabbit,
物种反应性
human, mouse
应用
electrophoretic mobility shift assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
抗磷酸化-STAT2 (Tyr689) 抗体, Upstate®, from rabbit,
物种反应性
human, mouse
应用
immunoprecipitation (IP)
inhibition assay
western blot
inhibition assay
western blot
Anti-phospho-STAT2 (pTyr690) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Stat2 (pTyr690) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Anti-STAT2 Antibody, Upstate®, from rabbit,
物种反应性
mouse
应用
electrophoretic mobility shift assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot