SPHK1
sphingosine kinase 1
别名:
SPHK
物种:
Human SPHK1 (8877), Mouse Sphk1 (20698), Rat Sphk1 (170897), Thale Cress SPHK1 (828239), Horse SPHK1 (100058875), domestic cat SPHK1 (101084918), dog SPHK1 (483329), domestic guinea pig Sphk1 (100727266), naked mole-rat Sphk1 (101711606), chicken SPHK1 (427803) ...展开
UniProtKB ID:
基因ID:
- Human(8877) Summary: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Mouse(20698) sphingosine kinase 1
- Rat(170897) sphingosine kinase 1
- Thale Cress(828239) sphingosine kinase 1
- Horse(100058875) sphingosine kinase 1
- domestic cat(101084918) sphingosine kinase 1
- dog(483329) sphingosine kinase 1
- domestic guinea pig(100727266) sphingosine kinase 1
- naked mole-rat(101711606) sphingosine kinase 1
- chicken(427803) sphingosine kinase 1
- cow(618605) sphingosine kinase 1
- sheep(101105263) sphingosine kinase 1
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Antibodies
货号
说明
物种反应性
应用
Anti-SPHK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, canine, human, mouse, rat
应用
ELISA
western blot
western blot
Monoclonal Anti-SPHK1 antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-SPHK1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Proteins
货号
说明
物种
Sphingosine kinase 1 Active human, recombinant, expressed in baculovirus, ≥80% (SDS-PAGE),
物种
human
Sphingosine kinase 1a Active from mouse, recombinant, expressed in baculovirus, ≥70% (SDS-PAGE),
物种
human
SPHK1, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human