SIGLEC5
sialic acid binding Ig-like lectin 5
- Human(8778) Summary: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
- Mouse(233186) sialic acid binding Ig-like lectin 5
- Rat(292843) sialic acid binding Ig-like lectin 5
- cow(100300478) sialic acid binding Ig-like lectin 5
- dog(476396) sialic acid binding Ig-like lectin 5
- naked mole-rat(101708758) sialic acid binding Ig-like lectin 5
- domestic cat(101094223) sialic acid binding Ig-like lectin 5
- domestic guinea pig(100736000) sialic acid binding Ig-like lectin 5
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